One Life, One Chance follows Cassian, a 20-year-old man who has already died three times. Each time he dies, he is reborn in a new timeline, retaining vague memories of his past lives, but unaware of how he dies or why the cycle continues. In his third life, he finds himself in a magical fantasy world, vastly different from his previous experiences. Though the faces are familiar, the settings and circumstances change, and Cassian struggles to form meaningful connections, knowing they will inevitably be lost.